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GMC · Engine · Moderate code

P0301 on GMC: How to Diagnose & Fix

Cylinder 1 Misfire Detected

6 GMC models · 7 documented issues · 6 critical · $400-$8,000 repair

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P0301 by GMC model

  • 2007-2020Yukon1
  • 2011-2020Sierra 2500HD2
  • 2010-2025Savana1
  • 2014-2023Sierra 15001
  • 2007-2019Yukon XL1
  • 2015-2025Canyon1
  • FAQ

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P0301 by GMC model

  • 2007-2020Yukon1
  • 2011-2020Sierra 2500HD2
  • 2010-2025Savana1
  • 2014-2023Sierra 15001
  • 2007-2019Yukon XL1
  • 2015-2025Canyon1
  • FAQ

P0301 on GMC by model: symptoms, diagnosis and fix

Community reported
1,480 owners
Link to this issueError Codes:P0300P06DDP0521P0301P0304P0306P0307

The GMC Yukon 5.3L (L83, LC9, LMG) and 6.2L (L94, L86) V8 engines use Active Fuel Management (AFM) cylinder deactivation. The special collapsible AFM lifters on cylinders 1, 4, 6, and 7 fail prematurely, causing misfires, engine ticking, rough idle, and potential catastrophic damage. This is the single most reported mechanical failure on GMT900 (2007-2014) and K2XX (2015-2020) Yukon models. GM issued TSB 18-NA-077 acknowledging the issue. Yukon models used as daily drivers with lots of highway cruising (where AFM activates most) are most susceptible. The VLOM (Valve Lifter Oil Manifold) must also be replaced as it controls oil flow to AFM lifters.

Common Symptoms

  • Misfire codes P0300, P0301, P0304, P0306, P0307
  • Engine tick or tap at idle that worsens with load
  • Rough idle or engine vibration
  • Check engine light
  • Reduced engine power / limp mode
  • Metal debris in oil (confirmed on drain plug inspection)
  • Vibration between 30-55 mph during V4 deactivation mode

How to Fix

Replace all 16 lifters, VLOM (GM 12639516), and inspect camshaft lobes. AFM delete kit (Texas Speed or BTR) permanently eliminates the system. Range Technology AFM Disabler RA003B prevents AFM activation as a preventive measure. Change oil every 5,000 miles with Dexos1 Gen 2 full synthetic to protect lifters.

Typical repair cost:$3,500 - $8,000
Sources for this issue (1)
  • NHTSA Campaign 11V007 - Rear-Axle Cross-Pin Recallrecall

Research This Issue

Based on 1,480 owner reports

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Community Reported
High Confidence1,480 owner reportsLast reported by owners Feb 2026Reviewed Feb 2026
All GMC Yukon known issues →
Community reported
640 owners
Link to this issueError Codes:P0171P0174P0300P0301P0302P0303P0304P0401P0404

The LML Duramax EGR (exhaust gas recirculation) cooler is prone to coolant leaks internally, allowing coolant to enter the intake manifold and combustion chambers. Coolant in the intake causes white smoke, rough running, and potential hydrolocking of cylinders. The EGR valve also sticks open or closed from carbon buildup, causing rough idle, black smoke, and check engine lights. The EGR cooler failure can occur as early as 60,000 miles on trucks used in stop-and-go driving. GM issued multiple TSBs addressing EGR cooler design improvements.

Common Symptoms

  • White smoke from exhaust especially on startup
  • Coolant loss with no visible external leak
  • Rough idle or engine misfire
  • Check engine light with EGR codes (P0401, P0404)
  • Coolant smell from exhaust
  • Overheating or coolant in oil (severe cases)
  • Black smoke and poor fuel economy (EGR valve stuck open)

How to Fix

Replace EGR cooler with updated GM design or aftermarket stainless steel unit (Mishimoto MMEGR-DMAX-LML). Clean or replace EGR valve. Flush cooling system and inspect for coolant contamination in intake. Consider EGR delete kit for off-road/race use only (illegal for street use). Prevent premature failure by maintaining proper coolant pH and avoiding extended idle periods.

Typical repair cost:$1,200 - $3,500
Sources for this issue (1)
  • NHTSA Campaign 23V047 - Sierra 2500 Rear Fuel Tankrecall

Research This Issue

Based on 640 owner reports

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Community Reported
High Confidence640 owner reportsLast reported by owners Feb 2026Reviewed Feb 2026
Community reported
430 owners
Link to this issueError Codes:P0300P06DDP0521P0301P0304P0306P0307

The 6.0L L96 V8 gasoline engine in Sierra 2500HD (non-diesel) suffers from Active Fuel Management (AFM) lifter failures similar to the 5.3L in Sierra 1500 — though less frequently due to the higher displacement. More commonly, 6.0L engines exhibit excessive oil consumption (1 qt per 1,000-3,000 miles) from worn valve stem seals and piston rings, particularly between 100,000-150,000 miles. The L96 is a high-output truck engine subjected to heavy towing and payload, which accelerates wear on AFM components.

Common Symptoms

  • Oil level dropping between changes (check every 1,000 miles)
  • Blue smoke on cold startup or under heavy acceleration
  • Spark plug fouling on AFM cylinders
  • Engine misfire codes P0300, P0301, P0304, P0306, P0307
  • Ticking from valvetrain (AFM lifter collapse)
  • Oil on spark plug threads

How to Fix

AFM disabler device (Range Technology RA003B) to prevent lifter wear. Oil consumption: GM oil consumption test procedure — if over 1 qt/2,000 miles, piston ring replacement authorized. Change oil every 5,000 miles with full synthetic Dexos2 5W-30. Valve stem seal replacement for blue smoke on startup.

Typical repair cost:$400 - $7,000
Sources for this issue (1)
  • NHTSA Campaign 24V060 - Sierra 2500 Power Tailgaterecall

Research This Issue

Based on 430 owner reports

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Community Reported
High Confidence430 owner reportsLast reported by owners Feb 2026Reviewed Feb 2026
All GMC Sierra 2500HD known issues →
Community reported
350 owners
Link to this issueError Codes:P0300P06DDP0521P0301P0304P0306P0307

GMC Savana vans equipped with 4.8L (L20), 5.3L (LM7), and 6.0L (L96) V8 engines with Active Fuel Management suffer the same AFM lifter collapse problem documented across the entire GM full-size truck/van lineup. The collapsible AFM lifters on deactivation cylinders fail between 60,000-120,000 miles, causing misfires, engine ticking, rough idle, and potential engine damage. Commercial Savana vans used for fleet operations are especially vulnerable due to high mileage accumulation and variable maintenance practices. The problem affects all GMT600 platform Savana/Express vans with AFM-equipped engines.

Common Symptoms

  • Misfire codes P0300, P0301, P0304, P0306, P0307
  • Ticking or tapping from engine
  • Rough idle especially when cold
  • Check engine light
  • Reduced power under load
  • Metal shavings on oil drain plug magnet

How to Fix

Replace all 16 lifters and VLOM (GM 12639516). AFM delete kit for permanent fix. Range Technology RA003B disabler for prevention. Increase oil change frequency to 5,000 miles with Dexos2 full synthetic for commercial use vans.

Typical repair cost:$3,500 - $8,000
Sources for this issue (1)
  • NHTSA Campaign 10V138 - Savana Generatorrecall

Research This Issue

Based on 350 owner reports

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Community Reported
High Confidence350 owner reportsLast reported by owners Feb 2026Reviewed Feb 2026
All GMC Savana known issues →
Community reported
345 owners
Link to this issueError Codes:P0171P0174P0300P0301P0302P0303P0304

Direct injection engines do not spray fuel over the intake valves like port injection systems, allowing carbon deposits from oil and blow-by gases via the PCV system to accumulate on intake valve backs and ports. Over time, this buildup restricts airflow causing performance and efficiency loss. The 5.3L and 6.2L engines with direct injection are susceptible to this issue typically after 60,000-100,000 miles.

Common Symptoms

  • Reduced fuel economy
  • Rough idle
  • Hesitation during acceleration
  • Engine misfires
  • Reduced power output
  • In severe cases, engine knock or pinging

How to Fix

Walnut shell blasting of intake valves (professional service). Chemical intake cleaning treatment. Install oil catch can to reduce PCV contamination. Manual intake manifold removal and valve cleaning.

Typical repair cost:$400 - $800
Sources for this issue (1)
  • NHTSA Campaign 19V837 - Fuel Pump Missing Pressure Regulator Recallrecall

Research This Issue

Based on 345 owner reports

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Community Reported
Medium Confidence345 owner reportsLast reported by owners Feb 2024Reviewed Feb 2026
All GMC Sierra 1500 known issues →
Link to this issueError Codes:P0300P0301P0306P0308

The Yukon XL with the 5.3L or 6.2L V8 and Active Fuel Management (AFM/DOD) system develops hydraulic valve lifter failures. The AFM lifters, which collapse to deactivate cylinders for fuel economy, fail and cause persistent ticking noise, misfires, and potential camshaft damage. The problem is most common on 2007-2019 models. GM service bulletin recommends replacing all 8 AFM lifters if ticking persists after oil change.

Common Symptoms

  • Ticking noise on cold start lasting 2 seconds to 10 minutes
  • Persistent engine tick at idle
  • Misfires on AFM-deactivated cylinders
  • Rough idle when AFM engages
  • Check engine light with misfire codes
  • Reduced fuel economy

How to Fix

Typical repair cost:$1,500 - $4,500
Sources for this issue (1)
  • NHTSA Campaign 03V019 - Fuel-Tank Impact Shield Recallrecall

Research This Issue

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Community Reported
Medium Confidence
All GMC Yukon XL known issues →
Link to this issueError Codes:P0300P0301P0304

The 3.6L V6 with Active Fuel Management experiences lifter failure where the AFM lifters collapse, causing misfires and a ticking noise. The collapsing lifter can damage the camshaft lobe if not addressed.

Common Symptoms

  • Ticking or tapping from engine
  • Misfire on specific cylinders
  • Check engine light
  • Rough idle

How to Fix

Replace failed lifters and inspect camshaft for damage. AFM delete kits are available that disable cylinder deactivation and replace all AFM lifters with standard lifters. Requires ECM tune to disable AFM.

Typical repair cost:$800 - $2,500
Sources for this issue (1)
  • NHTSA Campaign 24V237 - Canyon Front Hub Boltsrecall

Research This Issue

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Community Reported
Medium Confidence
All GMC Canyon known issues →

P0301 code reference

General diagnostic-code context. The code alone does not confirm a cause for your vehicle; use the applicable issue card and its sources.

Frequently asked questions

What does P0301 mean on a GMC?

P0301 stands for "Cylinder 1 Misfire Detected." P0301 means the engine computer detected a misfire specifically in cylinder 1 — the spark didn't ignite the fuel properly, or the fuel/air mix didn't burn as it should. The computer detects this by sensing tiny variations in crankshaft speed each time a cylinder fires. A misfire wastes fuel, raises emissions, and can damage the catalytic converter if it's severe or persistent (a flashing check engine light usually warns of active, converter-damaging misfires). Because the code points to one specific cylinder, the cause is usually an ignition, fuel, or compression problem isolated to that cylinder. On GMC it is documented across 6 models: Yukon, Sierra 2500HD, Savana, Sierra 1500, Yukon XL, Canyon.

What are the most common causes of P0301?

The most common causes of P0301 are: Worn or fouled spark plug in cylinder 1, Failed ignition coil or coil pack for cylinder 1, Faulty or clogged fuel injector for cylinder 1, Vacuum or intake air leak affecting that cylinder, Bad spark plug wire (on applicable engines), Low compression (worn rings, leaking or burnt valve, head gasket), Carbon buildup on intake valves, Wiring or connector fault to the coil or injector. The specific cause varies by vehicle.

How much does it cost to fix P0301 on a GMC?

Published repair estimates on GMC range from $400 to $8,000 depending on the model and root cause. If an issue mentions a recall or campaign, check your VIN with the manufacturer or NHTSA and confirm eligibility and coverage with a dealer.

Related codes

  • P0300 · Random/Multiple Cylinder Misfire Detected
  • P0302 · Cylinder 2 Misfire Detected
  • P0303 · Cylinder 3 Misfire Detected
  • P0304 · Cylinder 4 Misfire Detected
  • 00522 · Engine Coolant Temperature Sensor (G62): Open Circuit / Short to Positive (B+)
  • 16500 · Engine Coolant Temp. Sensor (G62): Implausible Signal
  • 16502 · Engine Coolant Temperature Sensor (G62): Signal too High
  • 16566 · Mass Air Flow Sensor Signal Too Low (VAG)

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Content compiled with AI assistance using NHTSA complaints, TSBs, and owner reports. May contain errors. Always verify with your vehicle's service manual.

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