P0305 on Lexus: How to Diagnose & Fix

P0305 stands for "Cylinder 5 Misfire Detected." This code means the engine control module detected a misfire on cylinder number 5, meaning that cylinder is not burning its air-fuel mixture properly on some combustion cycles. The computer senses misfires by watching for tiny fluctuations in crankshaft speed each time a cylinder fails to fire correctly. A misfire wastes fuel, can make the engine run rough or shake, and dumps unburned fuel into the exhaust, which can overheat and damage the catalytic converter. It generally points to a problem with spark, fuel delivery, or compression specifically affecting cylinder 5. On Lexus it is documented across 1 model: IS.

The most common causes of P0305 are: Worn or fouled spark plug on cylinder 5, Failed ignition coil or coil pack for cylinder 5, Faulty or clogged fuel injector on cylinder 5, Vacuum or intake air leak affecting that cylinder, Bad spark plug wire or boot (on applicable engines), Low compression from worn rings, valves, or head gasket, Carbon buildup or sticking valve on cylinder 5, Lean or rich fuel condition affecting the cylinder. The specific cause varies by vehicle.

Published repair estimates on Lexus range from $250 to $900 depending on the model and root cause. If an issue mentions a recall or campaign, check your VIN with the manufacturer or NHTSA and confirm eligibility and coverage with a dealer.